The aim of this study was to explore data from different families of compounds through the use of a variety of machine learning techniques. The robust quantitative structure-activity relationship (QSAR)-based models were developed to further guide in the quest for new potent anti-cardiovascular disease compounds. QSAR study was conducted on 1-Phenylsulfinyl-3-(pyridin-3-yl)naphthalen-2-ols and related compounds to determine their efficacy as anti-cardiovascular disease drugs. Multiple linear ...
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Aldosterone Synthase Inhibitors as Promising Treatments for ...
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Therefore, the inhibition of aldosterone synthase (CYP11B2), which is the ...
Mineralocorticoid Dependent Cardiovascular and Renal Diseases ... response
elements to either initiate or repress target gene .... These findings indicate the
potential involvement of .... 18-substituted progesterone derivatives like the
acetylene.
مقالات حاوی کلیدواژه "Cardiovascular diseases" - جویشگر علمی ...
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QSAR modeling of naphthalene derivatives for inhibition of aldosterone synthase
as potential target for cardiovascular diseases. نویسنده(گان): Ghasem ...
دوشنبه 12 مهر 1395 ساعت 19:53