Cancer is a collection of biological processes in the human body considered as one of the mostproblematic diseases. Oral cancer is one of the worlds most advanced stages cancer withconvenient access, because its existence is not the patients chance of being alive. The mechanisticand biological pathways study has helped better and faster prognosis and treatment of cancer. Inthis study, OSCC data were analyzed with genetrail 2, the major rout of estrogen signaling pathwayin cancer effect we ...