QSAR modeling of naphthalene derivatives for inhibition of aldosterone synthase as potential target for cardiovascular diseases

QSAR modeling of naphthalene derivatives for inhibition of aldosterone synthase as potential target for cardiovascular diseases

The aim of this study was to explore data from different families of compounds through the use of a variety of machine learning techniques. The robust quantitative structure-activity relationship (QSAR)-based models were developed to further guide in the quest for new potent anti-cardiovascular disease compounds. QSAR study was conducted on 1-Phenylsulfinyl-3-(pyridin-3-yl)naphthalen-2-ols and related compounds to determine their efficacy as anti-cardiovascular disease drugs. Multiple linear ...

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QSAR modeling of Quinoline derivatives as potential target for Hepatitis B virus

QSAR modeling of Quinoline derivatives as potential target for Hepatitis B virus

The goal of the present study is the exploration of data from different families of compounds through the use of a variety of machine learning techniques so that robust QSAR-based models can be developed to further guide in the quest for new potent Hepatitis B virus compounds. In this work quantitative structure-activity relationship (QSAR) study has been done on 6-chloro-4-(2-chlorophenyl)-3-(2-hydroxyethyl) quinolin-2(1H)-one and related compounds as Hepatitis B drugs. Multiple linear ...

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