In silico determination and validation of oprL structure and b cell epitopes as vaccine candidate in Pseudomonas aeruginosa

In silico determination and validation of oprL structure and b cell epitopes as vaccine candidate in Pseudomonas aeruginosa

Pseudomonas aeruginosa is an opportunistic, non-fermentative, gram-negative rod which is an important cause of nosocomial infection leading to septicemia and death. The mortality rate is higher than bacteremias caused by other gram-negative opportunistic pathogens. One of the most important features of the bacterium is its resistance to various antibacterial agents, and even newly developed antibiotics have failed to reduce the mortality rate associated with this organism. There is increasing ...

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Identification and validation of Outer membrane protein (OMP) P6 3D structure and its topology in Haemophilus influenzae

Identification and validation of Outer membrane protein (OMP) P6 3D structure and its topology in Haemophilus influenzae

Haemophilus influenzae is a common human respiratory tract pathogen, causing disease in both children and adults. The bacterium is an important cause of otitis media, the most common reason for children to receive antibiotic therapy. Outer membrane protein P6 is a member of the class of outer membrane proteins known as peptidoglycan-associated lipoproteins. First discovered in the mid-1980s, P6 is a promising vaccine antigen that has been the subject of extensive study. P6 has several features ...

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The Dimensions of Learning Organization Questionnaire (DLOQ): A Validation Study in a Korean Context

The Dimensions of Learning Organization Questionnaire (DLOQ): A Validation Study in a Korean Context

The purpose of this study is to assess the validity and reliability of themeasurement scores of the learning organization culture, the Dimensions ofLearning Organization Questionnaire (DLOQ), in a Korean context. Atotal of 1,529 cases from 11 firms in two major Korean conglomerates wereanalyzed. Rigorous translation procedures, including both forward andbackward processes, have been applied to ensure the relevance of thisinstrumentation in different cultural contexts. As the results of ...

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