In silico determination and validation of oprL structure and b cell epitopes as vaccine candidate in Pseudomonas aeruginosa

In silico determination and validation of oprL structure and b cell epitopes as vaccine candidate in Pseudomonas aeruginosa

Pseudomonas aeruginosa is an opportunistic, non-fermentative, gram-negative rod which is an important cause of nosocomial infection leading to septicemia and death. The mortality rate is higher than bacteremias caused by other gram-negative opportunistic pathogens. One of the most important features of the bacterium is its resistance to various antibacterial agents, and even newly developed antibiotics have failed to reduce the mortality rate associated with this organism. There is increasing ...

دریافت فایل

Functional Exposed Amino Acids of LamB as a vaccine candidate for Vibriosis

Functional Exposed Amino Acids of LamB as a vaccine candidate for Vibriosis

Vibriosis is one of the most serious infectious diseases in fish and shellfish. However, due to thediversity of pathogens and their complicated serotypes, the progress in vaccine developmentagainst Vibriosis has been slow. LamB proteins (or maltoporins) are a family of OMPs. It formsa betabarrel composed of three monomers and ensures the transport of maltose and maltodextrinin Gram-negative bacteria reported that recombinant Aeromonas hydrophila outer membraneprotein 48, which belongs to the ...

دریافت فایل