QSAR modeling of naphthalene derivatives for inhibition of aldosterone synthase as potential target for cardiovascular diseases

QSAR modeling of naphthalene derivatives for inhibition of aldosterone synthase as potential target for cardiovascular diseases

The aim of this study was to explore data from different families of compounds through the use of a variety of machine learning techniques. The robust quantitative structure-activity relationship (QSAR)-based models were developed to further guide in the quest for new potent anti-cardiovascular disease compounds. QSAR study was conducted on 1-Phenylsulfinyl-3-(pyridin-3-yl)naphthalen-2-ols and related compounds to determine their efficacy as anti-cardiovascular disease drugs. Multiple linear ...

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Health-related variables and its health promoting Lifestyle predictors in cardiovascular disease patients

Health-related variables and its health promoting Lifestyle predictors in cardiovascular disease patients

The principal cause for death in the world is cardiovascular disease which leads to the death of 71million people every year. Poor lifestyle is a contributing element in this regard. The present study aims at assessing the effects of health-related variables and lifestyle variables on the results of exercise in patience with cardiovascular disease. This is a cross sectional descriptive study. Patients were divided randomly into two groups based on the results of exercise stress test: positive ...

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